Abstracts of Recent DHFR Studies

  • Hoeltzli, S. D. and C. Frieden (1998) Refolding of 6-19F-Tryptophan Labeled E. coli Dihydrofolate Reductase in the presence of Ligand: a Stopped-Flow NMR Spectroscopy Study. Biochemistry, 37, 387-398.

  • Hoeltzli, S. D. and C. Frieden (1996) Real-time Refolding Studies of 6-19F-Tryptophan Labeled E. coli Dihydrofolate Reductase using Stopped-Flow NMR Spectroscopy. Biochemistry 35, 16843-16851.

  • Hoeltzli, S. D. and C. Frieden (1995) Stopped-Flow NMR Spectroscopy - Real-Time Unfolding Studies Of 6-19F-Tryptophan-Labeled Escherichia Coli Dihydrofolate Reductase. Proceedings of the National Academy of Sciences of the United States of America 92, 9318-9322.

  • Hoeltzli, S. D. and C. Frieden (1994) 19F NMR spectroscopy of 6-19F-tryptophan-labeled Escherichia coli dihydrofolate reductase: equilibrium folding and ligand binding studies. Biochemistry 33, 5502-9.

  • Hoeltzli, SD, Ropson, IJ and Frieden C. (1994) Application of equilibrium and stopped-flow 19F NMR spectroscopy to protein folding: Studies of E. coli dihydrofolate reductase. In: Techniques in Protein Chemistry VI (JW Crabb, Ed.) Academic Press, New York, pp. 455-465.