dept of biochemistry and molecular biophysics




Faculty

picture of Linda Kurz
Linda Kurz
 Research Professor - Emeritus
Dept. of Biochemistry and
Molecular Biophysics

Office: 212 McDonnell Science Building
Phone: 314-362-3401
Fax: 314-362-7183
Email: kurz@biochem.wustl.edu


Mailing Address:
WUSM - Biochemistry Dept.
660 S. Euclid Ave., MS8231
St. Louis, MO 63110



Research Interests

Macromolecular Interactions and Molecular Recognition



Selected Publications

  • Kurz, L.C., Fite, B., Jean, J., Park, J., Erpelding, T. and Callis, P. Photophysics of tryptophan fluorescence: Link with the catalytic strategy of the citrate synthase from Thermoplasma acidophilum. Biochem 44:1394-1413 (2005).
  • Kurz, L.C., Drysdale, G., Riley, M., Tomar, M.A., Chen, J., Russell, R.J.M. and Danson, M.J. Kinetics and Mechanism of the Citrate Synthase from the Thermophilic Archaeon, Thermoplasma acidophilum, Biochemistry 39:2283-2296 (2000).
  • Gu, Z., Drueckhammer, D.G., Kurz, L., Liu, K., Martin, D.P., and McDermott, A. Mechanism of Condensation Reaction of Citrate Synthase as Studied by Solid State NMR: Protonation States and Hydrogen Bonding Environment in the Binding Site of Acetylcoenzyme A Analog-Citrate Synthase Complexes. Biochemistry 38:8022-8031 (1999).
  • Deng, H., L.C. Kurz, et al. Characterization of hydrogen bonding in the complex of adenosine deaminase with transition state analogue: a Raman spectroscopic study. Biochemistry 37:4968-4976 (1998).
  • Kurz, L.C., T. Nakra, et al. Effects of changes in three catalytic residues on the relative stabilities of some of the intermediates and transition states in the citrate synthase reaction. Biochemistry 37:9724-9737 (1998).
  • Kurz, L. C., Roble, J.H., Nakra, T., et al. Ability of single-site mutants of citrate synthase to catalyze proton transfer from the methyl group of dethiaacetyl-coenzyme A, a non-thioester substrate analog. Biochemistry 36:3981-3990 (1997).

 

| Home | Biophysics Program | Graduate Programs | Courses | Faculty Directory | Research | Publications | Facilities | Grants | Mission Statement | Calendars & Reservations | People | Webmail | Center for Computational Biology | Events | Stockroom | Forms & Information | Employment | Biochemistry Computer Support |