Bio 5319 Molecular
Foundations of Medicine
Fall 2008
Tuesday and Thursdays,
8:30-10
Moore Auditorium
Lecture Number |
Date |
Topic |
Lecturer |
Reading |
I Tu |
Aug. 19 | Protein Structure I | Pike | Berg 2 |
II Th |
Aug. 21 | Enzyme Kinetics | Pike | Berg 8 |
III Tu |
Aug. 26 | Enzyme Kinetics/Allostery | Pike | Berg 10 |
IV Th |
Aug. 28 | Hemoglobin | Pike | Berg 7 |
V Tu |
Sep. 2 | Systemic Glucose Homeostasis | Pike | Berg 27 |
VI Th |
Sep. 4 | Glucose Homeostasis/Cell Signaling | Pike | Berg 14 |
VI-VII Tu |
Sep. 9 | G Proteins/Receptor Tyrosine Kinases |
Pike | Berg 14 Lodish 22 |
VII-VIII Th |
Sep. 11 | Receptor Tyrosine Kinases | Pike | Berg 14 Lodish 22 |
VIII Tu |
Sep. 16 | Hormonal Control of Fuel Sensing, Appetite and Body Weight | Fisher | |
IX-X Th |
Sep. 18 | Glycolysis (podcast) | Pike | Berg 16 |
XI Tu |
Sep. 23 | Gluconeogenesis/Glucose Sensing Pentose Phosphate Pathway |
Pike | Berg 16 Berg 20 |
XII Th |
Sep. 25 | TCA Cycle | Pike | Berg 17 |
XIII Tu |
Sept. 30 | ß-Oxidation of Fatty Acids | Pike | Berg 22 |
XIV Th |
Oct. 2 | Structure/Function of Mitochondria: Cardiomyopathy and Aging | Lehman | Berg 18 |
XV Tu |
Oct. 7 | Glycogen Metabolism | Pike | Berg 21 |
XVI Th |
Oct. 9 | Folate and B12 | Pike | Berg 24 |
| Monday | Oct. 13 | MIDTERM EXAM 9 am - 12 noon | ||
XVII Tu |
Oct. 21 | Nucleotide Metabolism | Pike | Berg 25 |
XVIII Th |
Oct. 23 | Transcription | Majors | Berg 29, 31 Lodish 10, 11 |
XIX Tu |
Oct. 28 | Translation | Majors | Berg 30 |
XX Th |
Oct. 30 | Fats, Phospholipids, and the Structure of Membranes | Pike | Lodish 5 Berg 12, 26 |
XXI Tu |
Nov. 4 | Biosynthesis and Processing of
Membrane Proteins |
Sadler | Lodish 17 |
XXII Th |
Nov. 6 | Synthesis Assembly
and Secretion of Proteins: Von Willebrand Factor as a Paradigm |
Sadler | Lodish 17 |
XXIII Tu |
Nov. 11 | Endocytosis |
Stahl | Lodish 17 |
XXIV Th |
Nov.13 | Lysosomes and Proteosomes | Stahl | Lodish 17 |
XXV Tu |
Nov. 18 | Microtubule Motors and Movements | Hodzic | Lodish 19 Berg 34 |
XXVI |
Nov. 20 | Cell-Cell and Cell-Matrix Interactions |
Frazier | Lodish 22 |
XXVII Tu |
Nov. 25 | Apoptosis | Weber | Lodish 24 |
Th |
Nov. 27 |
Thanksgiving Break |
||
XXVIII Tu |
Dec. 2 | Cell Cycle |
Weber | Lodish 13 |
XXIX Th |
Dec. 4 | Oncogenes and Tumor Suppressors |
Weber |
Lodish 23 |
XXX Tu |
Dec. 9 |
Nuclear Structure and DNA Replication |
Burgers |
Berg 28 |
XXXI Th |
Dec. 11 | DNA Replication and Repair | Burgers | Berg 28 |
Mon |
Dec. 15 | FINAL EXAM 9 am-12 noon |