Bio 5319 Molecular
Foundations of Medicine
Fall 2006
Tuesday and Thursdays,
8:30-10
Moore Auditorium
Lecture Number |
Date |
Topic |
Lecturer |
Reading |
| 1 Tu | Aug. 22 | Protein Structure I | Pike | Stryer 3 |
| 2 Th | Aug. 24 | Protein Structure II | Pike | Stryer 3 |
| 3 Tu | Aug. 29 | Enzyme Kinetics | Pike | Stryer 8 |
| 4 Th | Aug. 31 | Enzyme Kinetics/Allostery | Pike | Stryer 10 |
| 5 Tu | Sep. 5 | Hemoglobin | Pike | Stryer 10 |
| 6 Th | Sep. 7 | Systemic Glucose Homeostasis | Pike | Stryer 30 |
| 7 Tu | Sep. 12 | Glucose Homeostasis/Cell
Signaling |
Pike | Stryer 15 |
| 8 Th | Sep. 14 | Cell Signaling -
G Proteins Connor Auditorium |
Pike | Stryer 15 Lodish 22 |
| 9 Tu | Sep. 19 | Cell Signaling II - Receptor Tyrosine Kinases | Pike | Stryer 15 Lodish 22 |
| 10 Th | Sep. 21 | Glycolysis/Gluconeogenesis | Pike | Stryer 16 |
| 11 Tu | Sep. 26 | Pentose Phosphate Pathway and Glycogen Metabolism | Pike | Stryer 20,21 |
| 12 Th | Sep. 28 | TCA Cycle | Pike | Stryer 17 |
| 13 Tu | Oct. 3 | ß-Oxidation of Fatty Acids | Pike | Stryer 22 |
| 14 Th | Oct. 5 | Structure/Function of Mitochondria | Lehman | Stryer 18 |
| 15 Tu | Oct. 10 | Folates and B12 | Pike | Stryer 22 |
| 16 Th | Oct. 12 | Nucleotide Metabolism | Pike | Stryer 25 |
| Monday | Oct. 16 | MIDTERM EXAM 9 am - 12 noon | ||
| 17 Tu | Oct. 24 | Transcription | Majors | Stryer 28,31 Lodish 10 |
| 18 Th | Oct. 26 | Translation | Majors | Stryer 29 |
| 19 Tu | Oct. 31 | Structure of lipids, membranes and membrane proteins | Mueckler | Lodish 2,5 |
| 20 Th | Nov. 2 | Protein Biosynthesis, Molecular Chaperones, and Targeting to the RER | Mueckler | Stryer 29 Lodish 17 |
| 21 Tu | Nov. 7 | Biosynthesis of
Membrane Proteins |
Mueckler | Lodish 17 |
| 22 Th | Nov. 9 | Synthesis Assembly
and Secretion of Proteins: Von Willebrand Factor as a Paradigm |
Sadler | Lodish 17 |
| 23 Tu | Nov. 14 | Endocytosis |
Stahl | Lodish 17 |
| 24 Th | Nov.16 | Lysosomes and Proteosomes | Stahl | Lodish 17 |
| 25 Tu | Nov. 21 | Microtubule Motors and Movements | Dutcher | Lodish 19 |
| Th | Nov. 23 | Thanksgiving Break |
|
|
| 26 Tu | Nov. 28 | Cell-Cell and Cell-Matrix Interactions | Frazier | Lodish 22 |
| 27 Th | Nov. 30 |
Apoptosis |
Weber | Lodish 13 |
| 28 Tu | Dec. 5 | Cell Cycle |
Weber | Lodish 24 |
| 29 Th | Dec. 7 | Oncogenes and Tumor Suppressors |
Weber |
Lodish 23 |
| 30 Tu | Dec. 12 |
Nuclear Structure and DNA Replication |
Burgers |
Stryer 27 |
| 31 Th | Dec. 14 | DNA Replication and Repair | Burgers | Stryer 27 |
| Mon | Dec. 18 | FINAL EXAM 9 am-12 noon |