Overview
We are a biomedical research laboratory at Washington University School of Medicine under the direction of Tom Ellenberger. We are investigating the molecular structures and cellular functions of proteins that replicate DNA, repair chemical damage, and regulate chromatin structure. These enzymes and regulatory proteins are the "guardians of the genome," ensuring the faithful transmission of our genetic blueprint to future generations. Please see our Research Page and our Publications to learn more.
News
Positions are now available. Please see our Positions page for more information.
“On the cover of the July issue of Molecular Cell: Srs2 (blue) clears Rad51 filaments from ssDNA to downregulate homologous recombination. A specific interaction with the Rad51 filament, causing it to dissociate. Design by Amy VanDonsel. Antony et al. p. 105”. This work on the Srs2 helicase was a joint effort from members of the Ellenberger and Lohman groups.
